Glucose Tolerance Factor is an organic compound which contains trivalent chromium. The trivalent chromium participates in the process of delivering glucose inside cells and as such it plays a significant role in losing weight.
Insulin that circulates in the blood can stand in the way of weight loss. High insulin blood level prevents another enzyme from releasing fats from the adipose tissue. One of the ways of removing insulin from the blood is to make it attach to the surface of a cell where it plays a crucial role in the transfer of glucose inside the cells. The question is how to achieve that and the trivalent chromium is the answer.
Before the insulin can attach to the surface of a cell, a change in the spatial arrangement of the insulin receptor must occur. The order of events is following: 1. an oligopeptide attaches to the surface, 2. trivalent chromium attaches to the surface, 3. insulin attaches to the surface of the cell which is precisely what we need. (You can read another article explaining what happens when insulin attaches to the cell).
Insulin cannot attach to the surface if the oligopeptide and trivalent chromium are not attached to the cell already. This fact was discovered by two American scientists in 1997 and it is a milestone on the road of study of insulin physiological effect which began in the fifties.
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